Drug Interactions with Vardenafil (Levitra)
You should carry the list with you in case of emergencies. Vardenafil is a medication that treats erectile dysfunction. ED is the inability to achieve and sustain an erection suitable for sexual intercourse.
| Medication | Onset of Action | Duration | Common Side Effects | Cost |
|---|---|---|---|---|
| Levitra (Vardenafil) | 30-60 min | 4-5 hours | Headache, flushing | Moderate |
| Viagra (Sildenafil) | 30-60 min | 4-6 hours | Vision changes, headache | Slightly higher |
| Cialis (Tadalafil) | 30-60 min | Up to 36 hours | Muscle aches, flushing | Higher |
| Staxyn (Orally disintegrating) | 15-30 min | 4-5 hours | Similar to Viagra | Similar to Levitra |
This medication works by increasing blood flow to your penis, which helps you maintain an erection. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.
- Patients should avoid heavy meals and high-fat foods before taking Levitra.
- Levitra is generally safe but should not be combined with recreational drugs.
- It’s important to store Levitra in a cool, dry place out of children’s reach.
- Levitra’s effectiveness does not increase with higher doses; follow your doctor’s advice.
- Men with low blood pressure or severe cardiovascular issues should discuss risks beforehand.
- PDE5 inhibitors like Levitra do not protect against sexually transmitted infections.
- If no improvement in ED symptoms is seen after using Levitra, consult your doctor.
VARDENAFIL (var DEN a fil) treats erectile dysfunction (ED).
How Should I Store Them?
Do not use any of the medication from the pack if any of the blisters are torn, broken, or do not contain tablets. After you remove the tablet from the blister package, immediately place it on your tongue and close your mouth. If you need a higher or lower dose, your doctor may prescribe the regular tablets instead. Be sure that you receive only the type of vardenafil that was prescribed by your doctor. Ask your pharmacist if you have any questions about the type of vardenafil you were given.
Other Medical Problems
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. tell your doctor and pharmacist if you are allergic to vardenafil,any other medications. or any of the ingredients in vardenafil tablets. do not take vardenafil if you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others). Nitrates come as tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. It works by increasing blood flow to the penis, which helps to maintain an erection.
- Before using Levitra, inform your healthcare provider about all medical conditions.
- Levitra is not approved for use in women or children.
- It is important to follow the prescribed dosage to avoid side effects.
- Organic ED can often be improved through lifestyle changes alongside medication.
- Levitra can sometimes cause priapism, a painful prolonged erection requiring emergency care.
- Avoid grapefruit or grapefruit juice while taking Levitra, as it can affect drug levels.
- Levitra shows high efficacy in clinical trials, but individual responses may differ.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. They need to know if you have any of these conditions: Eye or vision problems, including a rare inherited eye disease called retinitis pigmentosa Heart disease, angina, a history of heart attack, irregular heart beats, or other heart problems History of blood diseases, such as sickle cell anemia or leukemia An unusual or allergic reaction to vardenafil, other medications, foods, dyes, or preservatives Take this medication by mouth with water.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Professional | 20mg | 30 Pills | 119.12€ 113.45€ | |
| Levitra Soft Tabs | 20mg | 120 + 8 Pills | 288.52€ 274.78€ | |
| Levitra Generic | 60mg | 270 + 10 Pills | 714.53€ 680.50€ | |
| Levitra Soft Tabs | 20mg | 90 + 6 Pills | 241.31€ 229.82€ | |
| Levitra Professional | 20mg | 90 + 2 Pills | 304.49€ 289.99€ | |
| Levitra Generic | 60mg | 10 Pills | 47.42€ 45.16€ | |
| Levitra Original | 20mg | 120 + 8 Pills | 528.19€ 503.04€ | |
| Levitra Generic | 10mg | 90 + 8 Pills | 150.58€ 143.41€ | |
| Levitra Original | 20mg | 4 Pills | 45.87€ 43.69€ | |
| Levitra Generic | 20mg | 120 + 10 Pills | 224.15€ 213.48€ | |
| Levitra Professional | 20mg | 360 + 6 Pills | 914.63€ 871.08€ | |
| Levitra Soft Tabs | 20mg | 180 + 10 Pills | 398.14€ 379.18€ | |
| Levitra Generic | 10mg | 60 + 6 Pills | 112.98€ 107.60€ | |
| Levitra Generic | 60mg | 360 + 10 Pills | 906.69€ 863.51€ | |
| Levitra Generic | 40mg | 10 Pills | 41.37€ 39.40€ | |
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Levitra Generic | 20mg | 360 + 10 Pills | 458.44€ 436.61€ |
Take it as directed on the prescription label.
- Levitra is effective for many men, but individual results can vary.
- Consultation with a healthcare provider helps determine appropriate use.
- Never share Levitra with others, as it is prescribed specifically for you.
- Levitra does not cure ED but effectively manages symptoms when used properly.
- Be aware of possible side effects like vision disturbances or allergic reactions.
- Regular checkups are recommended to monitor health during ED treatment.
- Always discuss other medications and supplements with your doctor before use.
The dose is usually taken 1 hour before sexual activity. You should not take this dose more than once per day. You can take it with or without food.
Vardenafil vs. Viagra vs. Cialis
do not take street drugs containing nitrates such as amyl nitrate and butyl nitrate ('poppers') while taking vardenafil. some medications should not be taken with vardenafil. Other medications may cause dosing changes or extra monitoring when taken with vardenafil. Make sure you have discussed any medications you are currently taking or plan to take before starting vardenafil with your doctor and pharmacist. Before starting, stopping, or changing any medications while taking vardenafil, please get the advice of your doctor or pharmacist.
Patient resources
the following herbal product may interact with vardenafil: St. John's wort. Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking vardenafil. Do not start any of these medications while taking vardenafil without discussing with your healthcare provider. tell your doctor if you smoke and if you have ever had vardenafil levitra an erection that lasted more than 4 hours. If it upsets your stomach, take it with food.
| Drug Category | Potential Interaction | Effect on Levitra Effect |
|---|---|---|
| Nitrates | Severe hypotension risk | Contraindicated |
| Alpha-blockers | Enhanced blood pressure lowering | Use caution, dose adjustment |
| Other PDE5 inhibitors | Increased side effects | Not recommended together |
| CYP3A4 inhibitors | Increased Levitra levels | Monitor for side effects |
Talk to your care team about the use of this medication in children. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you.
Who Should Not Take These?
Some patients experienced a sudden loss of some or all of their vision after they took vardenafil or other medications that are similar to vardenafil. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088). Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of unneeded medications in a way so that pets, children, and other people cannot take them.
Vardenafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
Do not flush this medication down the toilet. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website for more information. Keep all medication out of sight and reach of children as many containers are not child-resistant. Place the medication in a safe location – one that is up and away and out of their sight and reach. Do not share this medicine with others. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs.
What other information should I know?
Medically accurate: SingleCare’s Medical Review Board analyzes all of our content to confirm it’s in line with current medical advice. Evidence-based: Our content is sourced from reputable U.S.-based healthcare professionals and peer-reviewed research. Trustworthy: All of SingleCare’s content goes through a multi-phase review process by our writers, editors, and Medical Board in order to provide clear and credible information. Vardenafil is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Vardenafil is in a class of medications called phosphodiesterase (PDE) inhibitors.
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It works by increasing blood flow to the penis during sexual stimulation. Vardenafil does not cure erectile dysfunction or increase sexual desire. Vardenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Vardenafil comes as a tablet and a rapidly disintegrating (dissolves in the mouth and is swallowed without water) tablet to take by mouth. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Some items may interact with your medicine.
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In case of online levitra price overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Do not let anyone else take your medication. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking. Bring this list with you each time you visit a doctor or if you are admitted to the hospital. If you notice any changes in your vision while taking this medication, call your care team as soon as possible. Stop using this medication and call your care team right away if you have a loss of sight in one or both eyes. Contact your care team right away if the erection lasts longer than 4 hours or if it becomes painful.
Overdose/Missed Dose
Also tell your doctor if you have or have ever had a condition that affects the shape of the penis, such as angulation, cavernosal fibrosis, or Peyronie's disease; diabetes; high cholesterol; high or low blood pressure; irregular heartbeat; a heart attack; angina (chest pain); a stroke; ulcers in the stomach or intestine; a bleeding disorder; blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); seizures; and liver, kidney, or heart disease. Also tell your doctor if you or any of your family members have or have ever had long QT syndrome (a heart condition) or retinitis pigmentosus (an eye disease) or if you have ever had severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see. Tell your doctor if you have ever been advised by a health care professional to avoid sexual activity for medical reasons. Women should not take vardenafil, especially if they are or could become pregnant or are breast-feeding. tell all your health care providers that you are taking vardenafil.
Key Takeaways
If you ever need emergency medical treatment for a heart problem, the health care providers who treat you will need to know when you last took vardenafil. if you have fructose intolerance (an inherited condition in which the body lacks the protein needed to break down fructose,[a fruit sugar found in certain sweeteners such as sorbitol]), you should know that the the rapidly disintegrating tablets are sweetened with sorbitol. Tell your doctor if you have fructose intolerance. Talk to your doctor about eating grapefruit or drinking grapefruit juice while taking this medicine. erection that lasts longer than 4 hours sudden severe loss of vision (see below for more information) changes in color vision (seeing blue tinge on objects, difficulty telling the difference between blue and green, or difficulty seeing at night) swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs Call your doctor if you have any unusual problems while taking this medication. This may be a sign of serious problem and must be treated right away to prevent permanent damage. If you experience symptoms of nausea, dizziness, chest pain or arm pain upon initiation of sexual activity after taking this medication, you should refrain from further activity and call your care team as soon as possible. Drinking alcohol with this medication can increase the risk of side effects. Using this medication does not protect you or your partner against HIV or other sexually transmitted infections (STIs). Side effects that you should report to your care team as soon as possible: Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision Sudden vision loss in one or both eyes Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects.
- Levitra may not be effective for all forms of ED, especially psychological ED.
- Some men may develop a tolerance if used frequently over a long period.
- It’s important to follow the dosing schedule recommended by your doctor.
- Levitra should not be used as a recreational drug for performance enhancement.
- The safety of Levitra during pregnancy or breastfeeding has not been established.
- Lifestyle modifications can enhance the effectiveness of Levitra in ED treatment.
- Keep a record of your medication use and any side effects for medical review.
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